91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
黄色视频网站免费,成人性生交大免费看
Rabbit Anti-Nanog/Cy5.5 Conjugated antibody (bs-23500R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-23500R-Cy5.5
英文名稱 Rabbit Anti-Nanog/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的胚胎干細胞關(guān)鍵蛋白抗體
別    名 NANOG_HUMAN; Embryonic stem cell specific homeobox protein (Nanog); ENK; FLJ12581; FLJ40451; Homeobox transcription factor Nanog; Nanog homeobox; Homeobox protein NANOG; ES cell-associated protein 4; Early embryo specific expression NK-type homeobox protein; Homeobox transcription factor Nanog; Nanog; Ecat4.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  干細胞  細胞周期蛋白  細胞表面分子  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nanog
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Nanog is a newly identified homeodomain-bearing transcriptional factor. Nanog expression is specific to early embryos and pluripotential stem cells including mouse and human embryonic stem (ES) and embryonic germ (EG) cells. It is a key molecule involved in the signaling pathway for maintaining the capacity for self-renewal and pluripotency, bypassing regulation by the STAT3 pathway. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Nanog-deficient ES cells lose pluripotency and differentiate into extraembryonic endoderm lineage. Thus it is one of the molecular markers suitable for recognizing the undifferentiated state of stem cells in the mouse and human.
NANOG is a new marker for testicular carcinoma in situ and germ cell tumors.
NANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency. In other words, these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm).

Function:
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation.

Subunit:
Interacts with SMAD1 and SALL4.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and oocytes.

Similarity:
Belongs to the Nanog homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 100293888 Human

Entrez Gene: 79923 Human

Entrez Gene: 71950 Mouse

Omim: 607937 Human

SwissProt: Q9H9S0 Human

Unigene: 635882 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

研究表明;早期胚胎在沒有Nanog存在的情況下是不能存活的,但是這一蛋白的表達水平至今還有待于進一步研究。學(xué)者認為:Nanog依然是一種對于生殖細胞(germ lls)形成的必要因子,Nanog也是調(diào)控著細胞融合后的多重功能的關(guān)鍵因子。
胚胎干細胞是當(dāng)今生命科學(xué)和生物技術(shù)研究的熱點,這主要是由于其具有“發(fā)育全能性”的功能。ES能分化成人體200多種細胞類型,形成機體的任何細胞、組織和器官。通過掌握其分化發(fā)育的規(guī)律,在人工條件下定向分化為所需的細胞、組織乃至器官,科學(xué)家們希望可以用來治療目前還難以或無法治愈的帕金森氏病、早老性癡呆、白血病、糖尿病等頑癥,并且解決十分緊缺的組織和器官移植的來源問題,并且通過進一步與克隆技術(shù)相結(jié)合,運用體細胞核轉(zhuǎn)移技術(shù)來得到ES,還能解決細胞治療以及組織和器官移植的免疫排異難題。
版權(quán)所有 2004-2026 www.rvdoil.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
www.亚洲日韩欧美日韩久久久 | 久久99国产精品久久99爱酱 | 韩国无码视频在线观看 | 成人免费A级毛片无码片2023 | 一本大道HEYZO无码S99 | 国产一级一片免费播放放a 特级小箩利无套内谢A片 | 国产精品无码日韩18 | 免费一级视频在线观看 | 亚洲AV秘 无码聂小雨 | 午夜福利网站在线观看 | 国产精品99朵亚视频免费 | 亚洲精品成a人在线观看 | 国产哺乳奶水一区二区 | 少妇被c 黄 在线网站蜜桃 | 中国一级特黄真人高清aa大片 | 黄 色 成 人 视 频 | 国产一二三区在线观看 | 四川少妇搡BBBBB搡BBB | 久久久久亚州Av无吗A片 | 久久丰满人妻一区二区 | 苍井空一级婬片A片AAA片动漫 | 88欧美狠狠噜日日噜噜 | 国产又粗又猛视频免费h | 小12萝自慰喷白浆网站 | 专门看黄色视频的网站 | 成人黄色电影免费观看 | 一级A片高龄老妇毛多多 | 韩日产理伦片在线观看 | 特级西西444www大精品视频 | 中文字幕日本被黑人无码 | 91国语对白爽死我了第30集 | 白丝女仆被调教喷水免费视频 | 懂色av粉嫩av色欲av | 日本理论午牛夜理论片 | 精品无码国产污污污免费 | 亚洲精品国产色欲AV在线观看 | 欧美久久久久久一卡四 | 红桃视频成人A片免费播放 国产91 丝袜在线播放 | 视频丨9l 丨白浆 | 亚洲小说欧美激情另类A片小说 | 台湾佬中文综合娱乐网 |