產(chǎn)品編號(hào) | bs-24090R-Bio |
英文名稱 | Rabbit Anti-HJURP/Biotin Conjugated antibody |
中文名稱 | 生物素標(biāo)記的HJURP蛋白抗體 |
別 名 | 14-3-3-associated AKT substrate; FAKTS; fetal liver expressing gene 1; Fetal liver-expressing gene 1 protein; FLEG1; hFLEG1; HJURP; Holliday junction recognition protein; Up-regulated in lung cancer 9; URLC9. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 84kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse HJURP |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: HJURP is a 748 amino acid protein that is expressed in thymus, placenta, small intestine, liver, skeletal muscle, bone marrow and colon. When histone H3-like variant CENP-A nucleosomes are assembled, HJURP localizes in centromeres during late telophase and early G1 phase, and localizes to the nucleolus during S phase. Considered a centromeric protein, HJURP plays a central role in the incorporation and maintenance of CENP-A at centromeres. HJURP also acts as a specific chaperone for CENP-A and is required for the incorporation of newly synthesized CENP-A molecules into nucleosomes at replicated centromeres. HJURP is considered an indispensable factor for chromosomal stability in immortalized cancer cells and is a potential novel therapeutic target for the development of anticancer drugs. Function: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions. Subcellular Location: Nucleus; nucleolus. Centromere. Note: Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage. Database links:
Entrez Gene: 55355 Human
Entrez Gene: 381280 Mouse
Omim: 612667 Human
SwissProt: Q8NCD3 Human
SwissProt: Q6PG16 Mouse
Unigene: 532968 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 美女自慰喷水高清免费网站 | 午夜美乳高潮91精品 | 中文字幕av免费观看 | 精品无码一区二区三区在线朝桐光 | 成人 国产 免费观看爱豆传媒 | 国产又爽又黄无码无遮挡 | 一区二区三区在线免费看 | 亚洲日本无码一区二区在线二产线 | 色欲久久一区二区三区 | 91麻豆精品国产人妻一区二区三区 | 黄色视频在线免费无码观看 | 人人妻人人澡人人爽人人 | 国产高清视频一区二区 | 18禁网站禁片免费观看 | 欧美性 XX XX 图片 | 蜜桃视频网站一区二区三区 | 欧日韩精品福利在线观看 | 熟妇少妇自拍偷拍第五页 | 老女人的黄色视频, | 躁老太老太騷BBBB | 久久久久国产精品无码 | 亚洲色婷婷国产精品杨思敏 | 蜜桃无码人妻丰满熟妇区五十路i | 欧美一级特黄毛片免费 | 麻豆视频剧情短片在线观看 | 久久久人妻精品一区蜜桃 | 国产一级a毛一级a看免费视频野外 | 最好的观看2018在线 | 牛夜精品久久久久久久 | 大地资源国产精品系列 | 第一福利视频导航 | 中文字幕乱近親相姦886008 | 99在线无码精品秘 老外 | 人妻熟妇国产乱码精品精 | 日本无码人妻波多野结衣杨思敏 | 久久久无码精品人妻一区蜜桃网站 | 无套内射视频在线观看 | 亚洲熟妇AⅤ乱码在线 | 韩日产理伦片在线观看 | XXXX野外性XXXX黑人 |