| 產(chǎn)品編號 | bs-23826R-APC |
| 英文名稱 | Rabbit Anti-B4GALT2/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的B4GALT2抗體 |
| 別 名 | Beta-1,4-Galactosyltransferase 2; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 2; UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 2; Beta-1,4-GalTase 2; Beta4Gal-T2; B4Gal-T2; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1,4-Galactosyltransferase 2; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase, Polypeptide 2; UDP-Gal:BetaGlcNAc Beta 1,4-Galactosyltransferase, Polypeptide 2; UDP-Gal:BetaGlcNAc Beta 1,4- Galactosyltransferase 2; Beta-4-GalT2; EC 2.4.1.-; B4Gal-T3; B4GT2_HUMAN; |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 合成與降解 糖蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 42kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human B4GALT2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] Function: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose. Subcellular Location: Golgi apparatus Tissue Specificity: Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain. Similarity: Belongs to the glycosyltransferase 7 family. Database links: Entrez Gene: 8704 Human Entrez Gene: 53418 Mouse Omim: 604013 Human SwissProt: O60909 Human SwissProt: Q9Z2Y2 Mouse Unigene: 632403 Human Unigene: 123843 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
