產(chǎn)品編號(hào) | bs-23786R-Cy5 |
英文名稱(chēng) | Rabbit Anti-GPR43/Cy5 Conjugated antibody |
中文名稱(chēng) | Cy5標(biāo)記的G蛋白偶聯(lián)受體43抗體 |
別 名 | GPCR GPR43; FFA2R; Ffar2; FFAR2_HUMAN; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein coupled receptor 43; G protein-coupled receptor 43; G-protein coupled receptor 43; GPR 43; GPR43; GPCR 43. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse GPR43 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: G protein-coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor (GPR) GPR41 and GPR43 are related members of a homologous family of orphan G protein-coupled receptors that are tandemly encoded at a single chromosomal locus in both humans and mice. GPR43 functions as a ligand for short chain fatty acids (SCFAs), notably acetate and propionate. Bacteria in the gut produce high concentrations of SCFAs, which are subsequently released in the bloodstream, where they exert cellular effects on blood leukocytes, including calcium release, ERK1/2 activation, and inhibition of cAMP accumulation. These effects indicate a role for GPR43 in the recruitment of leukocytes, particularly polymorphonuclear cells, to sites of bacterial infection. Function: Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate. Subcellular Location: Cell membrane. Tissue Specificity: Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 2867 Human Omim: 603823 Human SwissProt: O15552 Human Unigene: 248056 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 91久久精品无码视频 | 黄色AV污污污大片在线看 | 国产 无码 又爽又刺激网站老师 | 免费无码婬AAAA片解说 | 特级西西444WWW大精品视频 | 五月婷婷乱伦海角出品 | 欧美国产一区二区 | 亚洲天堂无码视频 | 国产乱妇无乱码大黄AA片第1集 | 麻豆秘 在线观看国产 | 久久精品人妻无码一区二区三区网站 | 一区二区三区精密机械公司 | 国产又粗又长又黄又大的视频 | 中文字幕在线免费观看网站 | 手机在线看片av | 欧美夜间激情成人在线观看 | 免费 无码 国产真人视频九色 | 黄网站在线看免费入口 | 蜜桃视频在线无码观看女优 | 日韩精品无码人妻第一页 | 最新黄色视频在线播放 | 嫖妓老熟女嗷嗷叫91在线 | 精品一区二区三区蜜桃臀绯色 | 我丰满的岳 久久国产 | 婬片试看15分钟 | 性色av浪潮av| 亲子乱伦一区二区三区 | 无码少妇一级A片在线观看 9l视频自拍蝌蚪9l成人 | 国产精华一区久久久久 | 欧美四级成人版A片 | 成人在线观看免费 | 亚洲性av高清中文字幕 | 性感女性黄色免费观看视频破解版 | 特大巨人黑人AAA片BBC | av在线免费观看网址 | 美人少妇自慰多水成人A片一区 | 亚洲AV午夜成人片精品网站听书 | 欧美在线成人无码播放 | 国产精品在线久久三级片 | 91丨永久精品丨人妖 |