產(chǎn)品編號 | bs-21153R-BF488 |
英文名稱 | Rabbit Anti-RANBP17/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的RAN結(jié)合蛋白17抗體 |
別 名 | Exp 7; Exp7; Exportin 7; Exportin7; KIAA0745; RAN binding protein 16; RANBP 16; XPO 7; XPO7. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 結(jié)合蛋白 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Chimpanzee, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 124kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RANBP17 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002] Function: May function as a nuclear transport receptor. Subcellular Location: Cytoplasm. Nucleus. Nucleus > nuclear pore complex. Tissue Specificity: Highly expressed in testis, moderately in pancreas and weakly in other tissues studied. Similarity: Belongs to the exportin family. Database links: Entrez Gene: 739299 Chimpanzee Entrez Gene: 64901 Human Omim: 606141 Human SwissProt: Q9H2T7 Human Unigene: 410810 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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