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Rabbit Anti-HMG20A/PE Conjugated antibody (bs-18050R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18050R-PE
英文名稱 Rabbit Anti-HMG20A/PE Conjugated antibody
中文名稱 PE標記的高遷移率族蛋白20A抗體
別    名 FLJ10739; High mobility group 20A; High mobility group protein 20A; HM20A_HUMAN; HMG box containing protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain protein HMGX1; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; hmg20a; HMGX1; HMGXB1; Hypothetical protein FLJ10739; iBRAF; Inhibitor of BRAF35.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Rhesus monkey, Gorilla, Orangutan)
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HMG20A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 Function:
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 10363 Human

Entrez Gene: 513719 Cow

Entrez Gene: 487661 Dog

Entrez Gene: 100061369 Horse

Entrez Gene: 66867 Mouse

Entrez Gene: 100448723 Orangutan

Entrez Gene: 100156673 Pig

Entrez Gene: 714893 Rhesus monkey

Omim: 605534 Human

SwissProt: Q0VCL5 Cow

SwissProt: Q9NP66 Human

SwissProt: Q6NV87 Mouse

SwissProt: Q9DC33 Mouse

Unigene: 69594 Human

Unigene: 744173 Human

Unigene: 150856 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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