產(chǎn)品編號(hào) | bs-16322R-Gold |
英文名稱 | Rabbit Anti-phospho-GRLF1(Tyr1087)/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的磷酸化糖皮質(zhì)激素受體DNA結(jié)合因子1抗體 |
別 名 | GRLF1 (phospho Y1087); p-GRLF1 (phospho Y1087); ARHGAP35; GAP associated protein p190; Glucocorticoid receptor DNA binding factor 1; Glucocorticoid receptor DNA-binding factor 1; Glucocorticoid receptor repression factor 1; Glucocorticoid receptor repression factor 1; GRF 1; GRF-1; GRF1; GRLF 1; GRLF1; GRLF1_HUMAN; KIAA1722; MGC10745; p190 A; p190-A; P190A; P190A, rat, homolog of; p190ARhoGAP; p190RhoGAP; Rho GAP p190A; Rho GAP p190A; Rho GTPase-activating protein 35. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
產(chǎn)品類型 | 磷酸化抗體 |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 171kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human GRLF1 around the phosphorylation site of Tyr1087 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008] Function: Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor. Subcellular Location: Cytoplasm. Nucleus. Post-translational modifications: Tyrosine phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 4 FF domains. Contains 1 Rho-GAP domain. Database links: Entrez Gene: 2909 Human Entrez Gene: 232906 Mouse Omim: 605277 Human SwissProt: Q9NRY4 Human SwissProt: Q91YM2 Mouse Unigene: 509447 Human Unigene: 28646 Mouse Unigene: 400358 Mouse Unigene: 16508 Rat Unigene: 222475 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 丰满少妇一级毛片亚洲日韩 | 深圳妇女搡BBBB搡BBBB | 国产毛片中字幕视频看看 | 免费无码婬片AAAAA片 | 农村人伦一区二区三区 | 精品人妻一区二区三区蜜桃 | 国产精品无码中文字幕 | 亚洲AV无码成人片在线 | 少妇被又大又粗又爽毛片久久黑人 | 国产又粗又猛又爽又黄视频 | 国产人妻无码一区二区三区 | 三级片网站在线观看 | 免费一级a毛一级a看免费视频下载 | 亚洲精品一区二区三区四区高清 | 欧美BBBBB臊BBBBB. | 午夜成人电影在线观看 | 爆乳3把你榨干哦 | 国产欧美日韩一区二区三区 | 少妇人妻精品一区二区传媒蜜臀 | 91人妻人人澡人人爽人 | 四川少妇BBw搡BBBB槡BBBB 91精品国自产在线观看 | 女生可以看的黄色视频 | 精品日韩一区二区三区 | 蜜桃秘 无码一线二线三线av | 黑人巨大精品人妻一区二区 | 国产剧情亚洲无码视频 | 国产日韩AV免费 | 大蜜桃视频99爱精品a片 | 囯产精品久久久久久久久鸭脖高潮 | 欧美黑人一级爽快片婬片高清 | 美女裸舞一区二区 | 人妻蜜桃久久AV一区 | 免费白丝内内在线看 | 国产特黄无码A片免费看 | 成人做爰免费A片视频二机片91看片 | 安徽妇搡BBBB搡BBBB按摩小说 | 2025中文字幕无码视频 | 性一交一乱一A片久久99蜜桃 | 特级大胆西西4444人体 | 成人国产精品秘 久久 |