產(chǎn)品編號 | bs-16050R-PE-Cy5.5 |
英文名稱 | Rabbit Anti-FBXO44/PE-Cy5.5 Conjugated antibody |
中文名稱 | PE-Cy5.5標(biāo)記的FBXO44蛋白抗體 |
別 名 | 5730411K09; AV001623; DKFZp781J0852; F box gene 3; F box only protein 44; F box only protein 6a; F box protein 44; F box protein FBX30; F box/G domain protein 3; F-box only protein 44; F-box protein FBX30; F-box/G-domain protein 3; FBG3; FBX30; FBX44; FBX44_HUMAN; FBX6A; Fbxo44; Fbxo6a; MGC14140; RGD1562463. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 泛素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Pig, Cow, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 30kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FBXO44 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Subunit: Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with SKP1 and CUL1. Tissue Specificity: Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver. Similarity: Contains 1 F-box domain. Contains 1 FBA (F-box associated) domain. Database links: Entrez Gene: 93611 Human Entrez Gene: 230903 Mouse Omim: 609111 Human SwissProt: Q9H4M3 Human SwissProt: Q8BK26 Mouse Unigene: 556006 Human Unigene: 220327 Mouse Unigene: 401783 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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