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Rabbit Anti-GTF2A1 alpha/BF647 Conjugated antibody (bs-16410R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16410R-BF647
英文名稱 Rabbit Anti-GTF2A1 alpha/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的通用轉(zhuǎn)錄因子ⅡA亞基1/TFIIA-α抗體
別    名 General transcription factor IIA subunit 1; General transcription factor IIA1; Glucose regulated protein 58kD pseudogene; gtf2a1; TF2A1; TF2AA_HUMAN; TFIIA 42; TFIIA alpha p55; TFIIA alpha p55, isoform 1; TFIIA p35 subunit; TFIIA-42; TFIIAL; Transcription initiation factor IIA alpha chain; Transcription initiation factor IIA subunit 1; Transcription initiation factor TFIIA 42 kDa subunit.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35/42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTF2A1 alpha
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]

Function:
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

Subcellular Location:
Nucleus.

Post-translational modifications:
The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation.

Similarity:
Belongs to the TFIIA subunit 1 family.

Database links:

Entrez Gene: 2957 Human

Entrez Gene: 83602 Mouse

Entrez Gene: 83830 Rat

Omim: 600520 Human

SwissProt: P52655 Human

SwissProt: Q99PM3 Mouse

SwissProt: O08949 Rat

Unigene: 592334 Human

Unigene: 275728 Mouse

Unigene: 432242 Mouse

Unigene: 44436 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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