91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
91丨露脸丨熟女,国产一级一片免费播放放a
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-phospho-Ephexin-1 (Tyr179)/BF555 Conjugated antibody (bs-13084R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13084R-BF555
英文名稱 Rabbit Anti-phospho-Ephexin-1 (Tyr179)/BF555 Conjugated antibody
中文名稱 BF555標記的磷酸化神經(jīng)細胞鳥苷酸置換因子Ephexin1抗體
別    名 Ephexin-1 (phospho Y179); p-Ephexin-1 (phospho Y179); ARHGEF27; Eph-interacting exchange protein; EPHEXIN; Ephexin 1; Neuronal guanine nucleotide exchange factor; Ngef; NGEF_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領域 細胞生物  神經(jīng)生物學  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Ephexin-1 around the phosphorylation site of Tyr179
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.

Function:
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension.

Subunit:
Interacts with CDK5R1 and EPHA4; activated by EPHA4 through the CDK5 kinase.

Subcellular Location:
Cytoplasm. Membrane. Cell projection, growth cone. Associated with membranes. Localizes to axonal growth cones.

Tissue Specificity:
Highly expressed in brain specifically in caudate nucleus and to a lower extent in amygdala and hippocampus. Also detected in lung.

Post-translational modifications:
Src-dependent phosphorylation at Tyr-179 upon EPHA4 activation increases the guanine exchange factor activity toward RHOA.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
Database links : UniProtKB/Swiss-Prot: Q8N5V2.2

Database links:

Entrez Gene: 25791 Human

Entrez Gene: 53972 Mouse

Entrez Gene: 246217 Rat

Entrez Gene: 424744 Chicken

Omim: 605991 Human

SwissProt: Q8N5V2 Human

SwissProt: Q8CHT1 Mouse

SwissProt: Q5BKC9 Rat

Unigene: 97316 Human

Unigene: 435439 Mouse

Unigene: 20670 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.rvdoil.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
一级大黄A片三男一女 | 少妇激情一区二区三区久久大香香 | 午夜精品久久久久久久91蜜桃 | 91丨国产丨精品丨丝袜 | 91传媒无码一级精品片 | 五月天国产婷婷手机小视频 | 寡妇高潮一级毛片免费看 | 性爱69卖实少妇出规 | а天堂中文最新一区二区三区 | 国产做爰又粗又大又爽小妖精 | 精品女同一区二区三区在线绯色 | 欧妇槡BBBB槡槡BBBBB | 潘金莲一级婬片AAAAAA播放 | 国产裸体永久免费无遮挡 | 少妇搡BBBB搡BBB搡忠贞 | 波多野结衣被狂揉到高潮 | 91人妻无码精品蜜桃 | 亚洲无码免费观看 | 中文字幕 好色人妻av | 西西4444www大胆高清双腿 | 国产一区二区三区三区在线视频观看 | 久久 91 人妻交换 日韩欧美 | 西西人体A片无码视频 | 国产特级婬片免费看 | 欧美不卡一区二区 | 波多野吉衣无码内射精品视频 | 色琪琪一区二区三区亚洲区 | 特级西西4444WWW无码 | 特级西西444www大精品视频 | 国产做受免费无码A片国语 亚洲第一精品人人澡人人爽 | 国产精品 A片在线 | 北条麻妃42部无码电影 | 亚洲熟女av一区二区三区 | 成人在线免费观看视频 | 国产精品久久久久久无码欧美内衣 | 五月婷婷缴情丁香网 | 91国内精品久久久久精 | 91人妻互换一区二区三区 | 少妇搡BBBB搡BBB搡澳门 | 欧美日韩高清免费观看 | 农村嫖妓一区二区三区 |