91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
亚洲精品成人A片动漫,91在线无码精品秘 入口不卡
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO45/AP Conjugated antibody (bs-13150R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13150R-AP
英文名稱 Rabbit Anti-FBXO45/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的F-box蛋白45抗體
別    名 F box protein 45; F-box only protein 45; F-box/SPRY domain-containing protein 1; FBSP1_HUMAN; FBX45; fbxo45; hFbxo45.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發(fā)育生物學  信號轉導  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO45
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

Function:
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation.

Subunit:
Forms a complex with MYCBP2 and SKP1 but does not appear to form an authentic SCF (SKP1-CUL1-F-box protein) complex (By similarity). Interacts (via B30.2/SPRY domain) with TP73 (via SAM domain); leading to TP73 ubiquitination and degradation by proteasome. Interacts (via SRY domain) with UNC13A; leading to degradation of UNC13A by the proteasome (By similarity).

Subcellular Location:
Cell junction > synapse > postsynaptic cell membrane. Cell junction > synapse > presynaptic cell membrane.

Similarity:
Belongs to the FBXO45/Fsn family.
Contains 1 B30.2/SPRY domain.
Contains 1 F-box domain.

Database links:

Entrez Gene: 200933 Human

Entrez Gene: 268882 Mouse

Omim: 609112 Human

SwissProt: P0C2W1 Human

SwissProt: Q8K3B1 Mouse

SwissProt: P0CH38 Rat

Unigene: 169815 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.rvdoil.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
亚州精品一区二区三区黄久 | 亚洲欧美国产日韩综合 | 国产高清视频在线观看 | 做爰特黄AAAAAAA片 | 黄色成人网站在线浏览 | 国产福利电影在线观看 | 欧美日韩亚洲一区二区三区 | 扒开腿做爽爽爽白虎在线 | 国产精品秘 入勒来来来 | 蜜臀久久99精品久久久久 | 天天爱天天做天天大综合 | 台湾无码婬片A片AAA毛片 | 少妇w搡BBB搡BBB出血 | 人妻洗澡被强公日日视频无码动漫 | 久久久精品理论A级A片 | 97精品超碰一区二区三区 | 精品国产乱码久久久久久蜜柚 | 色鬼成人免费网站视频 | 成人久久视频免费观看 | 91丨九色丨丰满人妻 | JJZZJZZJZZ成熟人妻 | 乡下农村妇女一级毛片水多 | 欧美国产日韩一区二区 | 农村人伦一区二区三区 | 日本黄色视频在线观看 | 精品肉丝脚一区二区三区 | 日韩人妻丰满无码区A片 | EEUSS鲁丝少妇 | 中文乱码字幕人妻熟女人妻 | 91 黑料 精品 国产 | 黑丝美女高潮喷水免费网站 | 国产成人av一区二区三区在线 | 成人妇女免费播放久久久 | 精品国產理伦女人UV6 | 欧美寡妇性猛交XXX无码 | 真正的免费毛片网站 | 国产免费一区二区三区在线观看 | 欧美熟女AAAAA片 | 激情图片 激情小说 | 性一交一免一费一视一频 | 操美女视频在线观看 |