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Rabbit Anti-DRIL1/BF488 Conjugated antibody (bs-13031R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13031R-BF488
英文名稱 Rabbit Anti-DRIL1/BF488 Conjugated antibody
中文名稱 BF488標記的B淋巴細胞轉錄調節(jié)相關蛋白DRIL1抗體
別    名 ARI3A_HUMAN; ARID domain-containing protein 3A; ARID3A; AT rich interactive domain-containing protein 3A; AT-rich interactive domain-containing protein 3A; B cell regulator of IgH transcription; B-cell regulator of IgH transcription; Bright; dead ringer like 1; Dead ringer-like protein 1; DRIL1; DRIL3; E2F binding protein 1; E2F-binding protein 1; E2FBP1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  轉錄調節(jié)因子  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRIL1/ARID3A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

Function:
Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.

Subunit:
Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm.

Tissue Specificity:
Widely expressed, with highest expression in skeletal muscle, thalamus, and colon.

Similarity:
Contains 1 ARID domain.
Contains 1 REKLES domain.

Database links:

Entrez Gene: 1820 Human

Entrez Gene: 13496 Mouse

Entrez Gene: 314616 Rat

Omim: 603265 Human

SwissProt: Q99856 Human

SwissProt: Q62431 Mouse

Unigene: 501296 Human

Unigene: 301282 Mouse

nigene: 229683 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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