產(chǎn)品編號(hào) | bs-12194R-PE |
英文名稱 | Rabbit Anti-HOXB6/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的同源盒蛋白B6抗體 |
別 名 | HGNC:5117; homeo box B6; Homeobox protein Hox B6; Hox-2.2; HOX2; HOX2B; HU-2; HXB6_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from huuman HOXB6 (101-200aa) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: HoxB6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. HoxB6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. HoxB6 genes are also expressed in normal adult lung. Function: HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Subcellular Location: Nuclear Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 3216 Human Entrez Gene: 15414 Mouse Omim: 142961 Human SwissProt: P17509 Human SwissProt: P09023 Mouse Unigene: 98428 Human Unigene: 215 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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