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Rabbit Anti-ZIC5/RBITC Conjugated antibody (bs-12147R-RBITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12147R-RBITC
英文名稱 Rabbit Anti-ZIC5/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的鋅指蛋白ZIC5抗體
別    名 zic5; ZIC5_HUMAN; Zinc finger protein of the cerebellum 5; Zinc finger protein ZIC 5.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 68kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZIC5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13.

Function:
Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 4 C2H2-type zinc fingers.

Database links:

Entrez Gene: 85416 Human

Entrez Gene: 65100 Mouse

Entrez Gene: 361095 Rat

SwissProt: Q96T25 Human

SwissProt: Q7TQ40 Mouse

Unigene: 508570 Human

Unigene: 390761 Mouse

Unigene: 198356 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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