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Rabbit Anti-GPR88/Gold Conjugated antibody (bs-12017R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12017R-Gold
英文名稱 Rabbit Anti-GPR88/Gold Conjugated antibody
中文名稱 膠體金標記的G蛋白偶聯(lián)受體88抗體
別    名 G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; Probable G protein coupled receptor 88; STRG; Striatum specific G protein coupled receptor; GPR88_HUMAN; GPCR88.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein coupled receptor 88
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR88 (G protein-coupled receptor 88), also known as STRG, is a 384 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein coupled receptor family. Expressed exclusively in striatum, GPR88 functions as an orphan receptor that may be involved in signaling pathways throughout the cell. Human GPR88 shares 95% sequence identity with its rat counterpart, suggesting a conserved role between species.

Function:
An orphan receptor belonging to the G-protein coupled receptor 1 family, GPR88 is expressed almost exclusively in striatum.

Subcellular Location:
Cell Membrane; Multi-pass membrane protein

Tissue Specificity:
Expressed almost exclusively in striatum.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 54112 Human

Entrez Gene: 64378 Mouse

Entrez Gene: 64443 Rat

Omim: 607468 Human

SwissProt: Q9GZN0 Human

SwissProt: Q9EPB7 Mouse

SwissProt: Q9ESP4 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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