產(chǎn)品編號(hào) | bs-11936R-PE |
英文名稱 | Rabbit Anti-Plexin A4/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的神經(jīng)叢蛋白A4抗體 |
別 名 | FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4_HUMAN; PLXNA4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 210kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Plexin A4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons. Function: Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm Subunit: Interacts with NRP1 and NRP2 Subcellular Location: Cell membrane; Single-pass type I membrane protein Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the plexin family. Contains 4 IPT/TIG domains. Contains 3 PSI domains. Contains 1 Sema domain. Database links: Entrez Gene: 91584 Human Entrez Gene: 243743 Mouse Omim: 604280 Human SwissProt: Q9HCM2 Human SwissProt: Q80UG2 Mouse Unigene: 511454 Human Unigene: 444029 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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