| 產(chǎn)品編號(hào) | bs-11891R-AP |
| 英文名稱 | Rabbit Anti-Myotrophin/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的顆粒細(xì)胞分化蛋白抗體 |
| 別 名 | FLJ31098; FLJ99857; GCDP; Granule cell differentiation protein; MTPN; MTPN_HUMAN; Myotrophin; Protein V 1; Protein V-1; V 1; MTPN_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞分化 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from humam Myotrophin/GCDP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008] Function: Potential role in cerebellar morphogenesis. May function in differentiation of cerebellar neurons, particularly of granule cells. Seems to be associated with cardiac hypertrophy. Subunit: Interacts with RELA (By similarity). Interacts with the heterodimer formed by CAPZA1 and CAPZB. Subcellular Location: Cytoplasm (Probable). Nucleus (By similarity). Cytoplasm, perinuclear region (By similarity). Tissue Specificity: Ubiquitous. Similarity: Belongs to the myotrophin family. Contains 3 ANK repeats. Database links: Entrez Gene: 136319 Human Entrez Gene: 14489 Mouse Omim: 606484 Human SwissProt: P58546 Human SwissProt: P62774 Mouse SwissProt: Q7T2B9 Zebrafish Unigene: 602015 Human Unigene: 182746 Mouse Unigene: 3239 Rat Unigene: 75187 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
