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Rabbit Anti-HS6ST1/Gold Conjugated antibody (bs-11854R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11854R-Gold
英文名稱 Rabbit Anti-HS6ST1/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的硫酸乙酰肝素6腦苷脂轉(zhuǎn)硫酸酶1抗體
別    名 6OST 1; 6OST1; DKFZp547H098; FLJ25392; H6 ST1; H6ST 1; H6ST1_HUMAN; Heparan sulfate 6 O sulfotransferase 1; Heparan sulfate 6 sulfotransferase; Heparan sulphate 6 O sulphotransferase 1; Heparan-sulfate 6-O-sulfotransferase 1; HS6 ST1; HS6ST 1; HS6ST ; HS6ST-1; HS6ST1; MGC116899; MGC116901.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HS6ST1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969).

Function:
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.

Subcellular Location:
Membrane; Single-pass type II membrane protein

Tissue Specificity:
Expressed in fetal brain.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the sulfotransferase 6 family.

Database links:

Entrez Gene: 9394 Human

Entrez Gene: 50785 Mouse

Omim: 604846 Human

SwissProt: O60243 Human

SwissProt: Q9QYK5 Mouse

Unigene: 512841 Human

Unigene: 213566 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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