產品編號 | bs-4293R-BF488 |
英文名稱 | Rabbit Anti-MACC1/BF488 Conjugated antibody |
中文名稱 | BF488標記的結腸癌轉移相關蛋白1抗體 |
別 名 | 7A5; MACC1; MACC-1; MACC1_HUMAN; Metastasis associated in colon cancer 1; Metastasis-associated in colon cancer protein 1; Putative binding protein 7a5; SH3 domain-containing protein 7a5; SH3BP4L. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 腫瘤 免疫學 信號轉導 生長因子和激素 轉錄調節(jié)因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Human, Rat, (predicted: Mouse, Cow, ) |
產品應用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 94kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MACC1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: MACC1 is a key regulator of the hepatocyte growth factor(HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed19098908]).[supplied by OMIM]. Subunit: Interacts with FASLG. Subcellular Location: Cytoplasm. Nucleus. Note=Mainly found in the cytoplasm in non-metastasizing tumors. Tissue Specificity: Preferentially expressed in metastasizing tumors. Similarity: Contains 1 SH3 domain. Database links: Entrez Gene: 346389 Human Entrez Gene: 238455 Mouse Omim: 612646 Human SwissProt: Q6ZN28 Human Unigene: 598388 Human Unigene: 31376 Mouse Unigene: 81938 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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