產品編號 | bs-0449R-Gold |
英文名稱 | Rabbit Anti-TSLP/Gold Conjugated antibody |
中文名稱 | 膠體金標記的胸腺基質淋巴細胞生成素-1抗體 |
別 名 | Thymic stromal lymphopoietin isoform 1; Thymic stromal lymphopoietin; Thymic stromal lymphopoietin protein TSLP; TSLP protein; TSLP_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領域 | 細胞生物 免疫學 細胞因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human, ) |
產品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 15kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TSP-1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產品介紹 |
background: Thymic stromal lymphopoietin (TSLP) is a novel cytokine that was found to promote the development of murine B cells in vitro. This protein, which is expressed in a number of tissues including heart, liver and prostate, prevented apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ-3. Anti-interleukin (IL)-7 receptor antibodies (Abs) neutralized this effect indicating that TSLP binds to at least part of the IL-7 receptor complex. TSLP induced phosphorylation of signal transducer and activator of transcription (STAT)-5. Function: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. Subunit: Interacts with a receptor composed of CRLF2 and IL7R. Subcellular Location: Secreted. Tissue Specificity: Expressed in a number of tissues including heart, liver and prostate. Database links: Entrez Gene: 85480 Human Entrez Gene: 53603 Mouse Omim: 607003 Human SwissProt: Q969D9 Human SwissProt: Q9JIE6 Mouse Unigene: 389874 Human Unigene: 143716 Mouse Unigene: 201724 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胸腺基質淋巴細胞生成素-1(胸腺基質細胞分泌的淋巴細胞生成素-1) 為一種新型促進生長的細胞因子——胸腺基質淋巴蛋白(TSLP)可以引發(fā)炎癥反應, 這種炎癥反應可以引起很多過敏性疾病和哮喘。 TSLP可能是過敏性疾病最重要的引發(fā)劑,已得到科學家的重視,如果證實了 TSLP是一種起始因子,抑制TSLP可以有效地治療哮喘和其它過敏性疾病。 |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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