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Rabbit Anti-Proteasome 20S alpha 6/PE-Cy5.5 Conjugated antibody (bs-9355R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9355R-PE-Cy5.5
英文名稱 Rabbit Anti-Proteasome 20S alpha 6/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的蛋白酶體PSMα6抗體
別    名 27 kDa prosomal protein; HC2; IOTA; Macropain iota chain; Macropain subunit iota; Multicatalytic endopeptidase complex iota chain; p27K; PROS 27; PROS27; Prosomal P27K protein; Proteasome (prosome macropain) subunit alpha type 6; Proteasome iota chain; Proteasome subunit alpha type 1; Proteasome subunit alpha type 6; Proteasome subunit iota; PSMA6; PSA6_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal; proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber.

Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Subunit:
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, P-body (By similarity). Note=Co-localizes with TRIM5 in the cytoplasmic bodies (By similarity).

Similarity:
Belongs to the peptidase T1A family.

Database links:

Entrez Gene: 5687 Human

Entrez Gene: 26443 Mouse

Entrez Gene: 29673 Rat

Omim: 602855 Human

SwissProt: P60900 Human

SwissProt: Q9QUM9 Mouse

SwissProt: P60901 Rat

Unigene: 446260 Human

Unigene: 30210 Mouse

Unigene: 107278 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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