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Rabbit Anti-PACAP-38/Gold Conjugated antibody (bs-0200R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0200R-Gold
英文名稱 Rabbit Anti-PACAP-38/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的腺苷酸環(huán)化酶激活肽-38抗體
別    名 HSPC190; Proapoptotic Caspase Adaptor Protein; PACAP; pERp1; Plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; pituitary adenylate cyclase activating polypeptide; PRP-48; Pituitary adenylate cyclase-activating polypeptide 27; PACAP-related peptide; PACAP27; PACAP-27; Pituitary adenylate cyclase-activating polypeptide 38; Pituitary adenylate cyclase-activating polypeptide 38; PACAP38; PACA_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 5kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PACAP-38
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Pituitary adenylate cyslase Activating polypeptide-27/38, PACAP-27/38 is a neuropeptide that has substantial sequence homology to vasoactive intestinal peptide (VIP).Both VIPand PACAP-38are equipotent at the VCAP-2 receptor, while PAC AP -38 is equipotent to PACAP-27 and more potent than VIP at the PAC-1receptor. The function of PACAP is Stimulates adenylate cyclase in pituitary cells. It belongs to the glucagon family.

Function:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells.

Subunit:
Interacts with ADCYAP1R1 (via N-terminal extracellular domain).

Subcellular Location:
Secreted.

Similarity:
Belongs to the glucagon family.

Database links:

Entrez Gene: 116 Human

Entrez Gene: 11516 Mouse

Entrez Gene: 414283 Pig

Entrez Gene: 24166 Rat

Omim: 102980 Human

SwissProt: P18509 Human

SwissProt: O70176 Mouse

SwissProt: P41535 Pig

SwissProt: P13589 Rat

Unigene: 531719 Human

Unigene: 727476 Human

Unigene: 3407 Mouse

Unigene: 37400 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

腺苷酸環(huán)化酶激活肽是一種可激活垂體腺苷酸環(huán)化酶的多肽,有PACAP-27和 PACAP-38兩種形式,他們共同具有N端27個(gè)氨基酸,屬于PACAP/glucagon超級(jí)家族。在中樞神經(jīng)系統(tǒng)分布廣泛,其中以下丘腦含量最高。
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