產(chǎn)品編號 | bs-0008R-BF350 |
英文名稱 | Rabbit Anti-Nestin/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的巢蛋白/神經(jīng)上皮干細(xì)胞蛋白抗體 |
別 名 | ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; Nes; NEST_RAT; Nestin. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 心血管 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 細(xì)胞類型標(biāo)志物 腫瘤細(xì)胞生物標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 209kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from rat Nestin |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Nestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant marker for stem / progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS. Furthermore, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor. Function: Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. Subunit: Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, this protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3. Subcellular Location: cytoplasm Tissue Specificity: CNS stem cells. Post-translational modifications: Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized. Similarity: Belongs to the intermediate filament family. Database links: Entrez Gene: 10763 Human Entrez Gene: 18008 Mouse Omim: 600915 Human SwissProt: P48681 Human SwissProt: Q6P5H2 Mouse Unigene: 527971 Human Unigene: 331129 Mouse Unigene: 9701 Rat
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神經(jīng)干細(xì)胞標(biāo)志物 在動物體早期發(fā)育過程中,中樞神經(jīng)系統(tǒng)發(fā)育尤為重要 。Nestin是一種中等纖維蛋白,它在哺乳動物神經(jīng)前體細(xì)胞中表達(dá)較高,目前已被廣泛用于神經(jīng)前體細(xì)胞的重要標(biāo)志分子。研究Nestin的表達(dá)調(diào)控規(guī)律,將有助于人們認(rèn)識神經(jīng)前體細(xì)胞的生物特性。此抗體還表達(dá)中樞神經(jīng)系統(tǒng)干細(xì)胞及神經(jīng)上皮細(xì)胞。 |
| 精品蜜桃久久久久久久 | 亚洲精品一区中文字幕乱码 | 国产精品久久久久久无码 | 色诱大奶少妇在线看 | 91麻豆精品国产91久久久无限制版 | av中文字幕在线观看 | 国产老熟妇尿一尿精品播放一区区 | 四虎成人影视亚洲欧美 | 啊啊亚洲无吗视频免费 | 91亚洲精品久久久蜜桃 借种 | 少妇做受XXXXⅩ高潮片 | 五十路熟妇亚洲AV无码 | 日韩 欧美 在线观看 | 亚洲日韩精品视频在线 | 懂色AV 粉嫩AV 蜜乳AV | 亚洲一本在线电影av | 91在线无码精品秘 软件网站 | 国产成人精欧美黄色三级片精品 | 亚洲综合在线免费 | 成人片黄网站久久久免费 | 全免费一级毛片免费看无码播放 | 久久性爱高潮高清完整版免费观看 | 91久久精品一区二区别 | 2019中文在线高清观看电视剧 | 国产91农村毛片大全 | 国内自拍视频在线观看一区二区三区四区 | 四川BBB搡BBB搡多 | 国产乱人乱偷精品a人人澡 特黄三级又爽又粗又大洗澡 | 久久Av无码精品人妻系列试探 | AV无码在线观看 | 日韩精品无吗一区二区 | 国产乱码精品一区二区 | A片试看120分钟做受 | 五十路老熟妇一区二区三区 | 特级西西444www大胆高清图片 | 奶大灬舒服灬又爽灬高潮 | 无套内谢少妇毛片教师 | 国产精品久久久久久无码人妻 | 57pao国产成永久免费视频 | 久久久精品人妻一区二区三区蜜芽 |