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Rabbit Anti-AGFG1/RBITC Conjugated antibody (bs-8072R-RBITC)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-8072R-RBITC
英文名稱 Rabbit Anti-AGFG1/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的艾滋病病毒復(fù)制結(jié)合蛋白抗體
別    名 HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)菌及病毒  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AGFG1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication.

Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.

Subcellular Location:
Nucleus. Cytoplasmic vesicle.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
O-glycosylated (By similarity).

Similarity:
Contains 1 Arf-GAP domain.

Database links:

Entrez Gene: 536149 Cow

Entrez Gene: 3267 Human

Entrez Gene: 15463 Mouse

Entrez Gene: 363266 Rat

Omim: 600862 Human

SwissProt: Q2TA45 Cow

SwissProt: P52594 Human

SwissProt: Q8K2K6 Mouse

SwissProt: Q4KLH5 Rat

Unigene: 352962 Human

Unigene: 392569 Mouse

Unigene: 433409 Mouse

Unigene: 3734 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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