| 產(chǎn)品編號(hào) | bs-0214R-BF488 |
| 英文名稱 | Rabbit Anti-ICAD/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的Caspase激活的脫氧核糖核酸酶抑制劑抗體 |
| 別 名 | DFF-45 Beta; ICAD; ICAD L; ICAD S; Caspase activated deoxyribonuclease inhibitor short form; DFF 1; DFF 45; DFF-45; DFF alpha; DFF1; DFF35; DFF45; DFFA; Dffa DNA fragmentation factor, alpha subunit; DNA fragmentation factor 45 kDa subunit; DNA Fragmentation Factor Alpha Subunit; DNA fragmentation factor subunit alpha; DNA fragmentation factor, 45 kD, alpha subunit; DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1; A330085O09Rik; DNA fragmentation factor, 45kDa, alpha polypeptide; DNA fragmentation factor, alpha subunit; H13; Inhibitor of CAD; DFFA_HUMAN; Inhibitor of CAD; Inhibitor of Caspase Activated DNase; MGC143066; OTTHUMP00000001903; OTTHUMP00000001904; RP23 121D17.3;Inhibitor of Caspase Activated DNase. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 細(xì)胞凋亡 新陳代謝 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ICAD |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Caspase-activated deoxyribonuclease(CAD) also designated DNA fragmentation factor 45 kDa subunit (DFF-45)and Caspase-activated DNase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. ICAD (DNA fragmentation factor alpha subunit) (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) is inhibitor of the caspase-activated DNase (DFF44). Function: Inhibitor of the caspase-activated DNase (DFF40). Subunit: Heterodimer of DFFA and DFFB. Subcellular Location: Cytoplasm. Post-translational modifications: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. Similarity: Contains 1 CIDE-N domain. Database links: Entrez Gene: 1676 Human Omim: 601882 Human SwissProt: O00273 Human Unigene: 484782 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ICAD 是在細(xì)胞凋亡期誘導(dǎo)DNA分裂和染色體固縮的一種核酶，降解裸露的DNA 并誘導(dǎo)形態(tài)學(xué)變化。 |
