產(chǎn)品編號 | bs-2393R-BF488 |
英文名稱 | Rabbit Anti-TRPC6/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的瞬時受體電位離子通道蛋白6抗體 |
別 名 | MTRP6; Short transient receptor potential channel 6; si:rp71-1p14.9; Transient Receptor Potential Cation Channel Subfamily C Member 6; Transient receptor protein 6; TRP 6; TRP-6; TRP6; TRPC 6; TrpC6; TRPC6_HUMAN; TRRP6; bZ1P14.9; FLJ11098; FLJ14863; FSGS2. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 通道蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
產(chǎn)品應(yīng)用 | Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 106kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human TRPC6 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq]. Subunit: Interacts with MX1 and RNF24. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm. Similarity: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily. Contains 4 ANK repeats. Database links: Entrez Gene: 7225 Human Entrez Gene: 22068 Mouse Omim: 603652 Human SwissProt: Q9Y210 Human SwissProt: Q61143 Mouse Unigene: 159003 Human Unigene: 325086 Mouse Unigene: 105986 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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