產(chǎn)品編號 | bs-5013R-BF488 |
英文名稱 | Rabbit Anti-ABCG5/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的三磷酸腺苷結(jié)合轉(zhuǎn)運(yùn)蛋白G超家族成員5抗體 |
別 名 | ABCG5; ABCG5_HUMAN; ATP binding cassette sub family G (WHITE) member 5 (sterolin 1); ATP binding cassette sub family G member 5; ATP-binding cassette sub-family G member 5; Sterolin 1; Sterolin-1; STSL. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運(yùn)蛋白 結(jié)合蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 72kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ABCG5 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]. Function: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Subunit: May form heterodimers with ABCG8 or be tightly coupled to ABCG8 along a pathway regulating diatery-sterol absorption and excretion. Subcellular Location: Membrane; Multi-pass membrane protein (Probable). Tissue Specificity: Strongly expressed in the liver, lower levels in the small intestine and colon. DISEASE: Defects in ABCG5 are a cause of sitosterolemia (STSL) [MIM:210250]; also known as phytosterolemia or shellfish sterolemia. It is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterols including cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile. Sitosterolemia patients have hypercholesterolemia, very high levels of plant sterols in the plasma, and frequently develop tendon and tuberous xanthomas, accelerated atherosclerosis and premature coronary artery disease. Similarity: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. Contains 1 ABC transmembrane type-2 domain. Contains 1 ABC transporter domain. Database links: Entrez Gene: 64240 Human Omim: 605459 Human SwissProt: Q9H222 Human Unigene: 132992 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 白峰人妻系列在线观看 | 97人妻人人揉人人躁人人免费 | 中日韩精品A片日本有码 | 东京热av无码一区二区 | 色情婷婷国产在线视频 | 国产欧美一区二区三区精品酒店 | 午夜黄色视频高清无码 | 苍井空和黑人最猛一次 | 国产在线观看国产精品产拍 | 成人美妇一区二区三区 | 日本级婬乱片A片AAA毛片动漫 | 日本人做爰毛片免费播 | 内射毛片内射国产夫妻 | 国产伦精品一区二区三区视频新 | 黄免费在线观看高清国产 | 一牛影视文化传媒有限公司官网网站 | 亚洲色无色A片一区二区 | 丰满人妻日本久久久久 | 无码国产精品一区二区色情八戒 | 人人插人人妻人人爽 | 国产多毛XX毛茸茸毛多 | 午夜无码国产午夜 | 日韩成人在线啊啊啊 | 国产69精品久久久久久 | 亚洲第一页 在线 | 女同牲交免费视频 | 久久一区二区精品夜夜嗨 | 黄色片免费看的午夜 | 日本乳哺乳无码一区二区 | 无码 高潮 在线拍拍 | 欧美丰满人妻免费视频人 | 久久国产乱子伦精品一区二区小说 | 亚洲AV色香蕉国产天堂 | 嗳嗳视频在线观看无码 | 成人粉嫩蜜桃AV小网站 | 免费看黄色生活片。 | 黃色A片老师三級三級三級H野外 | 日韩视频免费在线观看 | 波多野结衣无码在线视频 | 白嫩小泬BBB免费观看 |