產(chǎn)品編號 | bs-4005R-PE |
英文名稱 | Rabbit Anti-ATG5/APG5L/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的自噬蛋白5/細(xì)胞凋亡的特異性蛋白抗體 |
別 名 | ATG5; APG 5; APG 5L; APG5; APG5 autophagy 5 like; APG5 like; APG5-like; APG5L; Apoptosis specific protein; Apoptosis-specific protein; ASP; ATG 5; ATG5; ATG5 autophagy related 5 homolog; Autophagy protein 5; hAPG5; Homolog of S Cerevisiae autophagy 5; ATG5_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞凋亡 細(xì)胞自噬 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 32kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human APG5L |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: In yeast, autophagy is an essential process for survival during nutrient starvation and cell differentiation. The process of autophagy is characterized as a non-selective degradation of cytoplasmic proteins into membrane stuctures called autophagosomes, and it is dependent on several proteins, including the autophagy proteins APG5 and APG7. Yeast Apg7 and the human homolog, APG7, share similarities with the ubiquitin-activating enzyme E1 in Saccharomyces cerevisiae and are likewise responsible for enzymatically activating the autophagy conjugation system. Apg5 and the human homolog, APG5 (also designated apoptosis-specific protein or APS), function as substrates for the autophagy protein Apg12. These proteins are covalently bonded together to form Apg12/APG5 conjugates, which are required for the progression of autophagy. Function: Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Subunit: The ATG5-ATG12 conjugate forms a complex with several units of ATG16. Interacts with TECPR1; the interaction is direct and does not take place when ATG16 is associated with the ATG5-ATG12 conjugate. Subcellular Location: Cytoplasm. Note=Colocalizes with nonmuscle actin. Tissue Specificity: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells. Post-translational modifications: Conjugated to ATG12; which is essential for autophagy, but is not required for association with isolation membrane. Similarity: Belongs to the ATG5 family. Database links: Entrez Gene: 9474 Human Entrez Gene: 11793 Mouse Omim: 604261 Human SwissProt: Q9H1Y0 Human SwissProt: Q99J83 Mouse Unigene: 486063 Human Unigene: 22264 Mouse Unigene: 98385 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 国产精品一区三区四区A片 欧美肥婆日逼视频免费播放 | 日本一级婬片AAAAAA片麻代 | 午夜福利伦伦电影理伦片 | 日韩欧美在线视频观看 | 人人妻人人澡人人dvd | 成人无码区免费A∨毛片 | 少妇高潮灌满白浆毛片免费看 | EEUSS鲁丝片一区二区三区不卡 | 全免费A级毛片免费看视频软件 | 婷婷五月天一区二区 | 人妻丰满熟妇av无码久久奶水 | 91在线无码精品秘 国产阿朱 | 欧美熟妇婬乱A片免费 | 在线观看黄色国产视频 | 国产太孟太爽太大太长视频 | 无码人妻一区二区三区免费京洛会 | 色婷婷日韩精品一区二区三区 | 性受 XXXX黑人XYX性爽 | 免费无遮挡 视频网站 | 爽 好大 快 奶国产片 | 国产精品嫩草久久久久yw193 | 国产无 码免费观看少萝 | 暖暖国产乱子伦视频 | 又黄又大又粗又大又硬 | 国产裸体视频BBBBB | 国产精品无码人妻无码色情多人 | 欧美成人精品一级A片青椒视频 | 亚洲精品巨爆乳无码大乳巨 | 无码AAAV级毛片日本一区二区 | 四川少妇XXXX做受内谢 | 免费看人妻换人妻互换A片 欧美成人午夜精品三级理论 | 亚洲AV无码乱码精品 | 伊人久久大香线蕉综合75 | 国产精华一区二区三区 | 免费一级视频在线观看 | 新91视频免费观看 | 国产91无套粉嫩白浆 | 亚洲成人一区二区三区 | 成人免费A片在线看 | 极品少妇无码高潮喷 |