產(chǎn)品編號(hào) | bs-2782R-AP |
英文名稱 | Rabbit Anti-CD44v5/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的CD44V5抗體 |
別 名 | CD44 antigen; CD44 molecule; Heparan sulfate proteoglycan; PGP1; CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MGC10468; MIC4; hematopoietic cell E- and L-selectin ligand; chondroitin sulfate proteoglycan 8; cell surface glycoprotein CD44; GP90 lymphocyte homing/adhesion receptor; heparan sulfate proteoglycan; hyaluronate receptor; Hermes antigen; homing function and Indian blood group system; epican; phagocytic glycoprotein 1; extracellular matrix receptor III. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 細(xì)胞粘附分子 細(xì)胞表面分子 糖蛋白 淋巴細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 85kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CD44v5 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. Function: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Subcellular Location: Membrane. Tissue Specificity: Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells. Post-translational modifications: Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors. N-glycosylated. O-glycosylated; contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s). Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672. Similarity: Contains 1 Link domain. Database links: Entrez Gene: 100034221 Horse Entrez Gene: 960 Human Entrez Gene: 12505 Mouse Omim: 107269 Human SwissProt: Q05078 Horse SwissProt: P16070 Human SwissProt: P15379 Mouse Unigene: 502328 Human Unigene: 423621 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 国产精品一级在线观看 | 91人妻人人做人碰人人爽九色-百度 | 欧美性爱视频在线播放 | 国内精品久久久久无码 | 国产9久视频在线观看9 | 成人性做爰全过程免费 | 国产午夜精品一区二区三区嫩草 | 色综合天天综合网国产成人网 | 天堂AV在线播放 | 精品国产AV一区二区 | 熟妇少妇自拍偷拍第五页 | 山东一级毛片免费观看 | 国产精品视频免费在线观看 | 人妻丝袜中文字幕在线 | 国产乱码一区二区三区 | 日本A一片中国A一片 | 在线观看免费黄色视频网站 | 真人做爰A片免费观看茄子视频 | 老女人的黄色视频, | 日本无码熟妇五十路视频 | 人妻熟女一区二区AⅤ天美 粉嫩Av绯色AV蜜乳AV | 欧美必出精品在线观看 | 久久婷婷的综合色丁香五月 | 大学生依人在线视频精品 | 精品乱码一区内射人妻无码 | 97人妻人人澡人人爽国产一 | 国产乱码一区二区三区 | 国产黄色视频在线观看播放 | 欧美人妻黑人无码国产 | 一区二区欧美xxBB | av中文字幕在线观看 | 无码人妻精品一区二区三 | 白洁老师国产麻豆片 | 影音先锋国产a v资源 | 色婷婷精品久久二区二区蜜 | 虎色视频成人版免费 | 蜜臀av粉嫩av色欲av | 大又大又粗又硬又爽少妇毛片 | 国产高清一级黄色电影 | 精品3D肉动漫A片在线 |