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Rabbit Anti-Acetyl Coenzyme A Carboxylase/Cy7 Conjugated antibody (bs-2745R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2745R-Cy7
英文名稱 Rabbit Anti-Acetyl Coenzyme A Carboxylase/Cy7 Conjugated antibody
中文名稱 Cy7標記的乙酰輔酶A羧化酶抗體
別    名 Acetyl Coenzyme A Carboxylase; ACAS2; AceCS; Acetate CoA ligase; Acetyl CoA synthetase; Acetyl coenzyme A synthetase cytoplasmic; Acetyl-CoA synthetase; ACS; ACSA; ACSS2; Acyl activating enzyme; Acyl CoA synthetase short chain family member 2; EC 6.2.1.1; MYH7B; ACAC; ACACB; ACC alpha; ACC beta; ACC1; ACC2; ACCA; ACCB; Acetyl CoA carboxylase 1; Acetyl CoA carboxylase 2; Acetyl CoA carboxylase alpha; Acetyl CoA carboxylase beta; Biotin carboxylase; COA1; COA2; HFA1; ACACB_HUMAN; ACACA_HUMAN; Acetyl Coenzyme A Carboxylase; Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Acetyl-CoA carboxylase 265; ACC-alpha; ACC-beta.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Cow, Monkey, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 265kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Acetyl Coenzyme A Carboxylase 1/2 (2307-2355aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Subunit:
Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.

Subcellular Location:
Endomembrane system. Note=May associate with membranes.

Tissue Specificity:
Predominantly expressed in the heart, skeletal muscles and liver.

Similarity:
Contains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain.
Contains 1 biotinyl-binding domain.
Contains 1 carboxyltransferase domain.

Database links:

Entrez Gene: 31 Human

Entrez Gene: 32 Human

Entrez Gene: 100705 Mouse

Entrez Gene: 107476 Mouse

Entrez Gene: 116719 Rat

Entrez Gene: 60581 Rat

Omim: 200350 Human

Omim: 601557 Human

SwissProt: O00763 Human

SwissProt: Q13085 Human

SwissProt: Q5SWU9 Mouse

SwissProt: O70151 Rat

SwissProt: P11497 Rat

Unigene: 160556 Human

Unigene: 234898 Human

Unigene: 44372 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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