91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
陕西少妇性生交BBBBBB,9l视频自拍蝌蚪9l成人
Rabbit Anti-HIPPI/Gold Conjugated antibody (bs-11697R-Gold)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11697R-Gold
英文名稱 Rabbit Anti-HIPPI/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的舞蹈癥相關(guān)相互作用蛋白1/雌激素相關(guān)受體樣蛋白1抗體
別    名 Dermal papilla derived protein 8; Dermal papilla-derived protein 8; DERP 8; DERP8; Esrrbl 1; Esrrbl1; ESRRBL1 protein; Estrogen related receptor beta like 1; Estrogen related receptor beta like protein 1; Estrogen-related receptor beta like 1; Estrogen-related receptor beta-like protein 1; FLJ10147; Hip1 Interacting Protein; HIP1 interacting protein HIPPI; Hip1 protein interactor; HIP1-interacting protein; HIPPI; Huntingtin interacting protein 1 interacting protein; Huntingtin interacting protein 1 protein interactor; Huntingtin-interacting protein-1 protein interactor; IFT 57; ift57; IFT57_HUMAN; Intraflagellar transport 57 homolog (Chlamydomonas); Intraflagellar transport 57 homolog; Intraflagellar transport protein 57 homolog; MHS4R2; Vestrogen related receptor beta like 1; Vestrogen-related receptor beta like 1; CDNA FLJ10147 fis clone HEMBA1003369.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  Alzheimer's  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HIPPI (331-429aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, which occur later in human life. Huntington’s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum. Polyglutamine expansion reduces the level of association between Hip-1 and Htt, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor). The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, which may contribute to the neuronal cell death observed in individuals diagnosed with Huntington’s disease. The human hippi gene maps to chromosome 3q13.13 and encodes a 429 amino acid protein.

Function:
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Subunit:
Component of IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20. Interacts with IFT20 and IFT88. Interacts with BLOC1S2 and RYBP. Interacts with HOMER1, possibly leading to prevent pro-apoptotic effects of IFT57 (By similarity). Interacts with HIP1. In normal conditions, it poorly interacts with HIP1, HIP1 being strongly associated with HTT. However, in mutant HTT proteins with a long poly-Gln region, interaction between HTT and HIP1 is inhibited, promoting the interaction between HIP1 and IFT57, leading to apoptosis. Interacts with BFAR. Interacts with chicken anemia virus protein apoptin.

Subcellular Location:
Cytoplasm, cytoskeleton, cilium basal body (By similarity). Note=Concentrates within the inner segment of cilia

Tissue Specificity:
Present in many tissues such as brain, thymus, lymph node, lung, liver, skin and kidney (at protein level).

Similarity:
Belongs to the IFT57 family.

Database links:
UniProtKB/Swiss-Prot: Q9NWB7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.rvdoil.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲午夜成人天堂精品 | 国产无码在线观看黄 | 国产 成年妇 视频下载 | 国产人妻精品一区二区三水牛影视 | 欧美三级午夜理伦三级中视频 | 91无码粉嫩小泬无套在线哈尔滨 | 17c精品麻豆一区二区免费 | 国产精品无码久久久久一区二区 | 久久久久免费毛A片免费一瓶梅 | 成年视频大全黄色毛片儿 | 午夜精品秘 一区二区三区 中文字幕av久久爽一区 | 国产亲子伦一级A片 | 国精品无码一区二区 | 日本91又粗又猛又大爽又黄少妇 | 国产伪娘系列曦曦白丝露出 | 30分钟免费婬片A片 黄色美女视频在线观看 | 中文字幕日韩精品无码内射 | 国产在线精品国自产拍 | 欧美日韩精品少妇极品 | 国产一区二区三区在线 | 亚洲一区二区三区在线 | 久久视频午夜福利电影 | 日韩AV电影在线观看 | 无码人妻国产一区二区 | 中午字幕在线观看 | 无码人妻久久久午夜一区二区三区 | 免费在线观看黄色视频 | 又大又长又粗又硬又黄又爽无遮挡 | 久久午夜夜伦鲁鲁片无码免费 | 成人午夜做爰高潮片免费吸气 | 边洗澡边被躁BD在线看 | 潘金莲一级婬片AAAAAA播放 | 国色天香www在线视频 | 黄色成人视频在线观看 | 国产91看片婬黄大片 | 老女人一区二区三区老牛免费视频 | 国产黄片在线免费观看 | 粉嫩AⅤ一区二区三区四区五区 | 91人妻人人做人人爽蜜臀 | www.com.黄色视频 | 五十路熟女人妻一区二区久久久 |