產(chǎn)品編號 | bs-11194R-BF594 |
英文名稱 | Rabbit Anti-OLIG2/BF594 Conjugated antibody |
中文名稱 | BF594標(biāo)記的少突膠質(zhì)細(xì)胞轉(zhuǎn)錄因子2抗體 |
別 名 | Basic domain helix loop helix protein class B 1; Basic helix loop helix protein class B 1; bHLHB1; bHLHe19; Class B basic helix loop helix protein 1; Class B basic helix-loop-helix protein 1; class E basic helix loop helix protein 19; Class E basic helix-loop-helix protein 19; Human protein kinase C binding protein RACK17; Olig2; OLIG2_HUMAN; Oligo2; Oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; Oligodendrocyte transcription factor 2; PRKCBP2; Protein kinase C binding protein 2; Protein kinase C binding protein RACK17; Protein kinase C-binding protein 2; Protein kinase C-binding protein RACK17; RACK17. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat, (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 32kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human OLIG2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain. Function: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. Subunit: Contains 1 basic helix-loop-helix (bHLH) domain. Subcellular Location: Nucleus. Cytoplasm. The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. Tissue Specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. DISEASE: Note=A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14;21)(q11.2;q22) with TCRA. Similarity: Contains 1 bHLH (basic helix-loop-helix) domain. Database links: Entrez Gene: 10215 Human Entrez Gene: 50913 Mouse Omim: 606386 Human SwissProt: Q13516 Human SwissProt: Q9EQW6 Mouse Unigene: 176977 Human Unigene: 37289 Mouse Unigene: 22121 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 国产黄色小视频在线观看 | 性感少妇婷婷四房播播 | 免费婬乱男女婬视频无遮 | 人人操人人爽人人妻 | 尤物少妇一二三区A片 | 蜜桃无码一区二高考教师 | 成人网站在线观看一区高清 | 在线观看黄色www视频 | 黄视频网站观看免费 | 日韩人妻无码精品 | 闷骚少妇高潮出水 | 黃色毛片A片免费高潮 | 老色鬼超碰无码综合传媒 | 久久午夜夜伦鲁鲁片免费 | 古装一级无遮挡一级毛片 | 精品无码一区二区三区在线朝桐光 | 蜜桃AV秘一区二区三区 | 又粗又深又猛又爽无遮挡 | 奶大灬好爽灬一进一出 | 日本三级在线视频 | 九一免费无码高清视频 | 国产亚洲色婷婷久久99精品 | 一本久道激情淫乱视频 | 欧美喷潮喷水失禁合集 | 欧美性爱激情一区二区三区 | 熟妇~x88AV海角社区 | 欧美精品日韩视频一区 | 17c在线观看视频国产 | 成人免费毛片 网站 | 一级黄色免费观看视频 | 国产精品久久久久久妇女6080 | 色婷婷AV一区二区三区之红樱桃 | 中文子幕妇女伦伦在线 | 亚洲人午夜射精精品日韩 | 久久久久久久久久久av | 91丨九色丨丰满熟女首页 | 欧美人体做爰大胆A片 | 免费AV网站观看 | 可以看的黄色视频网站 | 成人无码高清123区 丁香婷婷一区二区三区 |