| 產(chǎn)品編號(hào) | IHC0140H |
| 英文名稱 | Human HLA-C Ready-To-Use IHC Kit |
| 中文名稱 | 人組織相容性蛋白1即用型免疫組化試劑盒 |
| 別 名 | D6S204, HLA-C, HLA-JY3, HLAC, HLC-C, MHC, PSORS1 |
| 性 狀 | Lyophilized or Liquid |
| 種 屬 | Human |
| 應(yīng)用范圍 | Immunohistochemistry |
| 適用樣品基質(zhì) | FFPE tissue |
| 描述 | IHC0140H is a ready-to-use IHC kit for staining of HLA-C. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data. |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described Gene ID: 3107 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0140H (Human HLA-C IHC Kit).
Immunohistochemical analysis of paraffin embedded human lung carcinoma tissue slide using IHC0140H (Human HLA-C IHC Kit).
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