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PAX6, BF594 conjugated (bs-22254R-BF594)  
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100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-22254R-BF594
英文名稱 PAX6, BF594 conjugated
中文名稱 BF594標記的轉(zhuǎn)錄因子Pax6抗體
別    名 AN 2; AN antibody; AN2; Aniridia type II protein; D11S812E; MGC17209; MGDA; Oculorhombin; Paired box 6; Paired box gene 6 (aniridia keratitis); Paired Box Gene 6; Paired box homeotic gene 6; Paired box protein Pax-6; Paired box protein Pax6; PAX 6; PAX6; PAX6_HUMAN; Sey; WAGR.  
研究領域 發(fā)育生物學  神經(jīng)生物學  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 46kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAX6 :221-320/422 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Pax genes contain paired domains with strong homology to genes in Drosophila which are involved in programming early development. The PAX2 gene is expressed in primitive cells of the kidney, ureter, eye, ear, and central nervous system. More specifically, in human embryo sections, PAX2 is expressed in the optic vesicle and later in the retina, in the otic vesicle and later in the semicircular canals of the inner ear, and in mesonephros, metanephros, adrenals, spinal cord, and hindbrain. PAX2 mutations can be responsible for renal hypoplasia, either isolated or associated with various ophthalmologic manifestations ranging from retinal coloboma to microphthalmia. The gene which encodes Pax-2 maps to human chromosome 10q24.3-q25.1. Lesions in the PAX6 gene accounts for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The gene which encodes Pax-6 maps to human chromosome 11p13.

SWISS:
P26367

Gene ID:
5080

Database links:

Entrez Gene: 395943 Chicken

Entrez Gene: 286857 Cow

Entrez Gene: 5080 Human

Entrez Gene: 18508 Mouse

Entrez Gene: 25509 Rat

Entrez Gene: 30567 Zebrafish

Omim: 607108 Human

SwissProt: P47237 Chicken

SwissProt: Q1LZF1 Cow

SwissProt: P26367 Human

SwissProt: P63015 Mouse

SwissProt: P63016 Rat

SwissProt: P55864 Xenopus laevis

SwissProt: P26630 Zebrafish

Unigene: 270303 Human

Unigene: 611376 Human

Unigene: 33870 Mouse

Unigene: 3608 Mouse

Unigene: 89724 Rat

Unigene: 647 Xenopus laevis

Unigene: 24244 Zebrafish



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