| 產(chǎn)品編號 | bsm-41524M |
| 英文名稱 | Mouse Anti-Human IgM antibody |
| 中文名稱 | 小鼠抗人IgM單克隆抗體 |
| 別 名 | human Immunoglobulin M. 鼠抗人-IgM; |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | kDa |
| 檢測分子量 | |
| 性 狀 | Liquid |
| 免 疫 原 | Human IgM |
| 亞 型 | IgG2a |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
| 產(chǎn)品圖片 |
The binding ability of antigen to antibody was detected by direct ELISA. The enzyme-labeled antibody (Anti-Human IgM Antibody-HRP (Cat. bs-41524M) specifically binds to HIgM, and has no cross reaction or weak reaction with HIgG1, HIgG4, HIgA and IgG.
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