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Cytokeratin 9 Recombinant Rabbit mAb (bsm-52066R)  
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產(chǎn)品編號 bsm-52066R
英文名稱 Cytokeratin 9 Recombinant Rabbit mAb
中文名稱 細胞角蛋白9重組兔單抗
別    名 CK 9; CK-9; CK9; Cytokeratin-9; Cytokeratin9; EPPK; K1C9_HUMAN; K9; Keratin 9; Keratin; Keratin type I cytoskeletal 9; Keratin-9; Keratin9; KRT 9; KRT9; type I cytoskeletal 9.  
研究領域 細胞生物  信號轉導  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 4F8
交叉反應 Human,Rat (predicted: Mouse)
產(chǎn)品應用 WB=1:500-1000,IHC-P=1:100-500,IHC-F=1:50-200,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62 kDa
檢測分子量
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human Cytokeratin 9 protein (300-450aa) 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008]

Function:
May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.

Tissue Specificity:
Expressed in the terminally differentiated epidermis of palms and soles.

DISEASE:
Defects in KRT9 are a cause of palmoplantar keratoderma epidermolytic (EPPK) [MIM:144200]; also abbreviated as EHPPK. EPPK is a dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present with knuckle pads, thick pads of skin appearing over the proximal phalangeal joints.

Similarity:
Belongs to the intermediate filament family.

SWISS:
P35527

Gene ID:
3857

Database links:

Entrez Gene: 3857 Human

Omim: 607606 Human

SwissProt: P35527 Human

Unigene: 654569 Human



產(chǎn)品圖片
Sample: Lane 1: Rat Ear tissue lysates Lane 2: Human A431 cell lysates Primary: Anti-Cytokeratin 9 (bsm-52066R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 62 kDa Observed band size: 60 kDa
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