產(chǎn)品編號(hào) | bs-23909R |
英文名稱 | SHISA5 Rabbit pAb |
中文名稱 | SHISA5蛋白抗體 |
別 名 | pProtein shisa 5; Putative NF kappa B activating protein 120; Putative NFkB activating protein 120; Scotin; Shisa homolog 5(Xenopus laevis); SHSA5_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 26 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SHISA5: 51-150/240 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Function: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. Subunit: Interacts with PDCD6; PDCD6 can stabilze SHISA5. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane. DISEASE: Induced in a p53/TP53-dependent manner in response to cellular stress. SWISS: Q8N114 Gene ID: 51246 Database links: Entrez Gene: 51246 Human Omim: 607290 Human SwissProt: Q8N114 Human Unigene: 414579 Human |
產(chǎn)品圖片 | |
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