產(chǎn)品編號 | bs-23238R |
英文名稱 | CXCL10/IP10 Rabbit pAb |
中文名稱 | CXCL10趨化因子10/干擾素誘導(dǎo)蛋白10抗體 |
別 名 | 10 kDa interferon gamma induced protein; C7; Chemokine(C X C motif) ligand 10; Chemokine CXC motif ligand 10; Crg 2; CRG2; CXCL 10; CXCL10; gamma IP10; gIP 10; GIP10; IFI 10; IFI10; INP 10; INP10; Interferon activated gene 10; Interferon gamma induced cell line; Interferon inducible cytokine IP 10; MOB1; SCYB 10; SCYB10; Small inducible cytokine B10; Small inducible cytokine B10 precursor; Small inducible cytokine subfamily B(Cys X Cys) member 10; gamma-IP-10. |
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Specific References (1) | bs-23238R has been referenced in 1 publications.
[IF=4.493] Fan Jiahui. et al. Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis. J IMMUNOL RES. 2022;2022:2932837 IHC ; Human.
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研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 生長因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 10 kDa |
檢測分子量 | |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CXCL10/IP10: 29-70/98 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020] Function: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Subcellular Location: Secreted. Post-translational modifications: CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes. Similarity: Belongs to the intercrine alpha (chemokine CxC) family. SWISS: P02778 Gene ID: 3627 Database links: Entrez Gene: 3627 Human Entrez Gene: 15945 Mouse Omim: 147310 Human SwissProt: P02778 Human SwissProt: P17515 Mouse Unigene: 632586 Human Unigene: 877 Mouse Unigene: 10584 Rat |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Human liver cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CXCL10) Polyclonal Antibody, Unconjugated (bs-23238R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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