| 產(chǎn)品編號(hào) | bs-8693R |
| 英文名稱 | PTPLAD1 Rabbit pAb |
| 中文名稱 | 蛋白酪氨酸磷酸酶樣A結(jié)構(gòu)域蛋白1抗體 |
| 別 名 | B IND1; Butyrate induced protein 1; Butyrate induced transcript 1; FLJ90376; hB ind1; HSPC121; Protein tyrosine phosphatase like A domain containing 1; PTPLAD 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 表觀遺傳學(xué) G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PTPLAD1: 1-100/362 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PTPLAD1 is a component of Rac1-signaling pathways leading to the modulation of gene expression. It potentiates different effects of the small GTPase Rac1, such as c-Jun N-terminal kinase activation and transcriptional activity of nuclear factor kappaB (NF-kappaB).It plays a crucial role in HCV RNA replication and the propagation of JFH1 virus through interaction with viral and host proteins. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the very long-chain fatty acids dehydratase HACD family. Contains 1 CS domain. SWISS: Q9P035 Gene ID: 51495 Database links: Entrez Gene: 51495 Human Entrez Gene: 57874 Mouse SwissProt: Q9P035 Human SwissProt: Q8K2C9 Mouse Unigene: 512973 Human |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PTPLAD1) Polyclonal Antibody, Unconjugated (bs-8693R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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