| 產(chǎn)品編號(hào) | bs-4983R |
| 英文名稱 | TRIP Rabbit pAb |
| 中文名稱 | 腫瘤壞死因子受體相互作用蛋白抗體 |
| 別 名 | RING finger protein 206; RNF206; TRAF Interacting Protein; TRAIP; TRIP. |
| 研究領(lǐng)域 | 腫瘤 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞膜受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRIP: 201-300/469 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. Function: Inhibits activation of NF-kappa-B mediated by TNF. Subunit: Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex. Interacts with CYLD. Subcellular Location: Cytoplasm. Cytoplasm, perinuclear region. Similarity: Contains 1 RING-type zinc finger. SWISS: Q9BWF2 Gene ID: 10293 Database links: Entrez Gene: 10293 Human Omim: 605958 Human SwissProt: Q9BWF2 Human Unigene: 517972 Human |
