產(chǎn)品編號 | bs-19615R |
英文名稱 | SEC23IP Rabbit pAb |
中文名稱 | SEC23相互作用蛋白抗體 |
別 名 | CDA II; CDAII; CDAN2; HEMPAS; Protein transport protein Sec23B; RP11-379J5.1; SC23B_HUMAN; Sec23 homolog B(S. cerevisiae); SEC23 related protein B; SEC23-like protein B; SEC23-related protein B; Sec23b; Transport protein SEC23B. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat,Rabbit,Sheep (predicted: Human,Mouse,Cow,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 111 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SEC23IP: 811-910/1000 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011] Function: Plays a role in the organization of endoplasmic reticulum exit sites. Subcellular Location: Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum. Tissue Specificity: Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle. Similarity: Belongs to the PA-PLA1 family. Contains 1 DDHD domain. Contains 1 SAM (sterile alpha motif) domain. SWISS: Q9Y6Y8 Gene ID: 11196 Database links: Entrez Gene: 11196 Human Entrez Gene: 207352 Mouse SwissProt: Q9Y6Y8 Human SwissProt: Q6NZC7 Mouse Unigene: 435004 Human Unigene: 667094 Human Unigene: 297105 Mouse |
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