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Kinectin 1 Rabbit pAb (bs-17064R)  
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產(chǎn)品編號 bs-17064R
英文名稱 Kinectin 1 Rabbit pAb
中文名稱 驅(qū)動蛋白受體KTN1抗體
別    名 CG1; CG1 antigen; KIAA0004; Kinectin; Kinesin receptor; KNT; KTN; KTN1_HUMAN; KTN1; MU-RMS-40.19.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 156 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Kinectin 1: 1201-1300/1357 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012]

Function:
Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.

Subcellular Location:
Endoplasmic reticulum membrane. Plasma membrane.

Tissue Specificity:
High levels in peripheral blood lymphocytes, testis and ovary, lower levels in spleen, thymus, prostate, small intestine and colon.

Similarity:
Belongs to the kinectin family.

SWISS:
Q86UP2

Gene ID:
3895

Database links:

Entrez Gene: 3895 Human

Entrez Gene: 16709 Mouse

Entrez Gene: 361029 Rat

Omim: 600381 Human

SwissProt: Q86UP2 Human

SwissProt: Q61595 Mouse

Unigene: 509414 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat ovarian); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Kinectin 1) Polyclonal Antibody, Unconjugated (bs-17064R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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