產(chǎn)品編號(hào) | bs-16924R |
英文名稱(chēng) | KCTD1 Rabbit pAb |
中文名稱(chēng) | 鉀離子通道多聚體結(jié)構(gòu)域蛋白1抗體 |
別 名 | BTB/POZ domain-containing protein KCTD1; C18orf5; Kctd1; KCTD1_HUMAN; Potassium channel tetramerisation domain containing 1; Potassium channel tetramerization domain-containing protein 1. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 29 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KCTD1: 201-257/257 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
KCTD1 (potassium channel tetramerisation domain containing 1), also known as C18orf5, is a 257 amino acid protein that contains one BTB domain, suggesting an involvement in transcriptional control. The gene encoding KCTD1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Function: May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. Subcellular Location: Nucleus. Tissue Specificity: Expressed in mammary gland, kidney, brain and ovary. Post-translational modifications: Sumoylated. Similarity: Contains 1 BTB (POZ) domain. SWISS: Q719H9 Gene ID: 284252 Database links: Entrez Gene: 284252 Human Omim: 613420 Human SwissProt: Q719H9 Human Unigene: 526630 Human |
產(chǎn)品圖片 | |
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