| 產(chǎn)品編號 | bs-14346R |
| 英文名稱 | DMRT1 Rabbit pAb |
| 中文名稱 | DMRT1蛋白抗體 |
| 別 名 | DM domain expressed in testis 1; DM domain expressed in testis protein 1; DMRT 1; dmrt1; DMRT1_HUMAN; DMT 1; DMT1; Doublesex and mab 3 related transcription factor 1; Doublesex-and mab-3-related transcription factor 1. |
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Specific References (1) | bs-14346R has been referenced in 1 publications.
[IF=8.025] Chang Shu. et al. Function of Foxl2 and Dmrt1 proteins during gonadal differentiation in the olive flounder Paralichthys olivaceus. INT J BIOL MACROMOL. 2022 Aug;215:141 WB ; Fish.
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| 研究領(lǐng)域 | 細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DMRT1: 31-130/373 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008] Function: May be required for testis development. Subcellular Location: Nucleus. Tissue Specificity: Testis specific. Similarity: Belongs to the DMRT family. Contains 1 DM DNA-binding domain. SWISS: Q9Y5R6 Gene ID: 1761 Database links: Entrez Gene: 1761 Human Omim: 602424 Human SwissProt: Q9Y5R6 Human Unigene: 98586 Human |
