產(chǎn)品編號 | bs-13031R |
英文名稱 | DRIL1 Rabbit pAb |
中文名稱 | B淋巴細(xì)胞轉(zhuǎn)錄調(diào)節(jié)相關(guān)蛋白DRIL1抗體 |
別 名 | ARI3A_HUMAN; ARID domain-containing protein 3A; ARID3A; AT rich interactive domain-containing protein 3A; AT-rich interactive domain-containing protein 3A; B cell regulator of IgH transcription; B-cell regulator of IgH transcription; Bright; dead ringer like 1; Dead ringer-like protein 1; DRIL1; DRIL3; E2F binding protein 1; E2F-binding protein 1; E2FBP1. |
研究領(lǐng)域 | 腫瘤 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞分化 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 63 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DRIL1/ARID3A: 201-300/593 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008] Function: Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. Subunit: Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK. Subcellular Location: Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm. Tissue Specificity: Widely expressed, with highest expression in skeletal muscle, thalamus, and colon. Similarity: Contains 1 ARID domain. Contains 1 REKLES domain. SWISS: Q99856 Gene ID: 1820 Database links: Entrez Gene: 1820 Human Entrez Gene: 13496 Mouse Omim: 603265 Human SwissProt: Q99856 Human SwissProt: Q62431 Mouse Unigene: 501296 Human Unigene: 301282 Mouse nigene: 229683 Rat |
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