產(chǎn)品編號(hào) | bs-12909R |
英文名稱(chēng) | BTN2A1 + BTN2A2 Rabbit pAb |
中文名稱(chēng) | 嗜乳脂蛋白2亞型A1抗體 |
別 名 | BK14H9.1; BT2.1; BT2A1_HUMAN; BT2A2_HUMAN; BTF1; BTN2A1; Butyrophilin BTF1; Butyrophilin subfamily 2 member A1; CTA-14H9.1; DJ3E1.1. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 新陳代謝 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 57 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human BTN2A1 + BTN2A2: 21-120/527 <Extracellular> |
亞 型 | |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Butyrophilin is a glycoprotein that is specifically expressed on the apical surface of mammary epithelial cells during lactation and becomes incorporated as an integral protein into the membrane of the milk fat globule during the budding and secretion of fat droplets into milk. BTN2A1 (butyrophilin subfamily 2 member A1), also known as BTF1, is a 527 amino acid single-pass type I membrane B box protein that plays a role in fatty-acid, sterol and lipid metabolism. A member of the immunoglobulin superfamily and BTN/MOG family, BTN2A1 exists as three alternatively spliced isoforms found at high levels in brain, muscle, spleen, pancreas, bone marrow and small intestine. BTN2A1 is expressed at moderate levels in kidney, liver and lung, and is encoded by a gene that maps to human chromosome 6p22.1. Subcellular Location: Membrane; Single-pass type I membrane protein (By similarity). Tissue Specificity: Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney. Similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 B30.2/SPRY domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q7KYR7 Gene ID: 11120 Database links: Entrez Gene: 11120 Human Omim: 613590 Human SwissProt: Q7KYR7 Human Unigene: 159028 Human |
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