| 產(chǎn)品編號(hào) | bs-12115R |
| 英文名稱 | DNER Rabbit pAb |
| 中文名稱 | 腦表皮生長(zhǎng)因子跨膜蛋白DNER抗體 |
| 別 名 | Brain EGF repeat-containing transmembrane protein; Bret; delta and Notch-like epidermal growth factor-related receptor; delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞表面分子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 75 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNER: 185-300/737 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. Function: Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. Subunit: Interacts with AP1G1. Interacts with NOTCH1. Subcellular Location: Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region. Tissue Specificity: Expressed in brain, spinal cord and adrenal gland. Similarity: Contains 10 EGF-like domains. Contains 1 follistatin-like domain. SWISS: Q8NFT8 Gene ID: 92737 Database links: Entrez Gene: 92737 Human Entrez Gene: 227325 Mouse Omim: 607299 Human SwissProt: Q8NFT8 Human SwissProt: Q8JZM4 Mouse Unigene: 234074 Human Unigene: 292560 Mouse |
