| 產(chǎn)品編號 | bs-11503R |
| 英文名稱 | SORCS3 Rabbit pAb |
| 中文名稱 | 液泡蛋白分選受體SORCS3抗體 |
| 別 名 | 6330404A12Rik; KIAA1059; RP11 107L7.1; SORC3_HUMAN; SORCS 3; SORCS; SORCS3; Sortilin related VPS10 domain containing receptor 3; VPS10 domain containing receptor SorCS3; VPS10 domain receptor protein SORCS 3; VPS10 domain-containing receptor SorCS3. |
| 研究領(lǐng)域 | 細胞生物 神經(jīng)生物學(xué) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 132 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SORCS3: 201-300/1222 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in brain. Similarity: Belongs to the VPS10-related sortilin family. SORCS subfamily. Contains 6 BNR repeats. Contains 1 PKD domain. Gene ID: 22986 Database links: UniProtKB/Swiss-Prot: Q9UPU3.2 |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SORCS3) Polyclonal Antibody, Unconjugated (bs-11503R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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