產(chǎn)品編號 | bs-11479R |
英文名稱 | SEMA4G Rabbit pAb |
中文名稱 | 跨膜蛋白SEMA4G抗體 |
別 名 | SEM4G_HUMAN; sema domain immunoglobulin domain(Ig) transmembrane domain(TM) and short cytoplasmic domain(semaphorin) 4G; Sema4g; semaphorin 4G; Semaphorin 4G precursor; Semaphorin-4G. |
研究領(lǐng)域 | 細胞生物 神經(jīng)生物學(xué) 細胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 90 kDa |
檢測分子量 | |
細胞定位 | 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SEMA4G: 71-120/838 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4G (semaphorin-4G) is an 838 amino acid single-pass type I membrane protein that is thought to play a role in axon guidance. Existing as three alternatively spliced isoforms, SEMA4G contains one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single SEMA domain. Function: Cell surface receptor for PLXNB2. May play a role in axon guidance. Subunit: Interacts with PLXNB2 Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 PSI domain. Contains 1 Sema domain. SWISS: Q9NTN9 Gene ID: 57715 Database links: Entrez Gene: 57715 Human SwissProt: Q9NTN9 Human Unigene: 591923 Human Unigene: 735152 Human |
產(chǎn)品圖片 | |
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