91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
www视频在线观看网站,欧美成人午夜无码A片秀色直播,风流少妇A片一区二区蜜桃
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Miz1/ZNF60 Rabbit pAb (bs-11234R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11234R
英文名稱(chēng) Miz1/ZNF60 Rabbit pAb
中文名稱(chēng) 鋅指蛋白60抗體
別    名 Miz-1; Myc-interacting zinc finger protein 1; Myc-interacting zinc finger protein; ZBT17; ZBT17_HUMAN; Zbtb17; Zinc finger and BTB domain containing protein 17; Zinc finger and BTB domain-containing protein 17; Zinc finger protein 151; Zinc finger protein 60; ZNF151; ZNF60.  
Specific References  (2)     |     bs-11234R has been referenced in 2 publications.
[IF=1.26] Liu et al. Increased expression of Myc-interacting zinc finger protein 1 in APP/PS1 mice. (2017) Exp.Ther.Med. 14:5751-5756  IHC-P ;  Mouse.  
[IF=1.2] Liu, Lu, et al. "Increased expression of Myc?interacting zinc finger protein 1 in APP/PS1 mice." Experimental and Therapeutic Medicine.  IHC-P ;  Mouse.  
研究領(lǐng)域 腫瘤  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 88 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Miz1/ZNF60: 331-430/803 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1; however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.

Function:
May function as a housekeeping DNA-binding protein that regulates the expression of specific genes. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Also has potent growth arrest activity, probably through inhibition of cell cycle progression. Required for early embryonic development during gastrulation.

Subunit:
Homooligomerizes (via the BTB/POZ domain), multimerization is required for DNA binding. Interacts (via the C-terminal zinc fingers) with GIF1; the interaction results in the recruitment of MYB to the CDKN1A/p21 and CDKN1B promoters and repression of transcription. Interacts with TRAF2, interfering with the binding of UBC13 to TRAF2, and inhibiting TRAF2 E3 ligase activity (By similarity). Interacts with MYC (via the C-terminal helix-loop-helix motif): the interaction inhibits ZBTB17 transactivation and growth arrest activities and renders it insoluble in the nucleus. Also interacts with HCFC1, MAGEA4 and TMPRSS11A.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 1 BTB (POZ) domain.
Contains 13 C2H2-type zinc fingers.

SWISS:
Q13105

Gene ID:
7709

Database links:
UniProtKB/Swiss-Prot: Q13105.3

版權(quán)所有 2004-2026 www.rvdoil.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
少妇搡bbbb搡bbb | 国产妇女野外牲一级毛片 | 特级大胆西西4444人体 | 91蜜桃传媒吹潮粉嫩少妇 | 波多野结衣高潮到受不了 | 免费的黄色视频网站下载在线 | 国产精品久久久18 成人 | 69精品国产人妻国产毛片 | 操东北妇女高潮视频 | 高清欧美性猛交XXXX黑人猛交 | 高清无码免费观看 | 久久精品人人人人人人 | 波多野佶衣中文字幕久久 | 美女A片18禁视频 | 老熟女又肥又大黑BBB | 亚洲va在线观看 | 成人在线视频免费 | 国产精品人妻一期二期三期四期 | 年轻少妇A片免费观看 | 亂倫近親相姦中文字幕网站 | 搡老女人老91妇女沈阳 | 拔丝袜午夜网址免费观看 | 久久国产精品视频 | 亚洲AV无码A片在线观看蜜桃 | 美女裸体视频一区二区 | 国产麻豆HDvideo无码 | 国产精品9999 | 久久久国产精品免费A片蜜 欧美性猛交 XX 乱下载 | 在线免费永久观看黄网站 | 亚洲天堂在线观看视频 | 国产真实乱婬A片三区高 | 91色秘 乱码一区二区三区竹菊 | 亚洲AV无码国产精品久久 | 国产精品高潮美女老师 | 欧美一区二区三区爽爽 | 99久久久无码国产精品免费四季 | 又大又长又粗又硬又黄又爽无遮挡 | 国产第一A片成人网站777 | 中文字幕人妻熟女人妻洋洋 | 影音先锋成人AV资源 | 亚洲AV无码乱码精品国产竹菊 |